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Biomimetic peptide‐enriched electrospun polymers: A photoelectron and infrared spectroscopy study
Author(s) -
Iucci G.,
Ghezzo F.,
Danesin R.,
Modesti M.,
Dettin M.
Publication year - 2011
Publication title -
journal of applied polymer science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.575
H-Index - 166
eISSN - 1097-4628
pISSN - 0021-8995
DOI - 10.1002/app.34768
Subject(s) - nanofiber , electrospinning , polymer , copolymer , materials science , fourier transform infrared spectroscopy , polymer chemistry , adhesion , peptide , chemical engineering , x ray photoelectron spectroscopy , infrared spectroscopy , fibronectin , side chain , extracellular matrix , chemistry , nanotechnology , organic chemistry , composite material , biochemistry , engineering
Biomimetic polymer nanofibers of poly(ε‐caprolactone) and poly( L ‐lactide–caprolactone) copolymer were prepared by electrospinning. Modifications of the polymer nanofibers aimed at improving their biomimetic properties were performed by two different routes: (1) immobilization of an adhesion peptide, which mimicked the adhesion sequence of the extracellular matrix protein fibronectin, on the polymer surface and (2) incorporation of self‐complementary oligopeptides, which showed alternated hydrophilic and hydrophobic side chain groups and was capable of generating extended ordered structures by self‐assembling, into the polymer nanofibers. The structure of the polymer/peptide nanofibers was investigated by X‐ray photoelectron and Fourier transform infrared spectroscopies. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2011