Synthesis, extraction, and anti‐bacterial studies of some new bis‐1,2,4‐triazole derivatives part I

A series of new bis triazole Schiff base derivatives (4) were prepared in good yields by treatment of 4‐amino‐3,5‐diphenyl‐4 H ‐1,2,4‐triazole (3) with bisaldehydes (1). Schiff bases (4) were reduced with NaBH 4 to afford the corresponding bisaminotriazoles (5). All the new compounds were characterized by IR, 1 H NMR and 13 C NMR spectral data. Their overall extraction (log K ex ) constants for 1 : 1 ( M : L ) complexes and CHCl 3 /H 2 O systems were determined at 25 ± 0.1°C to investigate the relationship between structure and selectivity toward various metal cations. The extraction equilibrium constants were estimated using CHCl 3 /H 2 O membrane transfer with inductively coupled plasma‐atomic emission spectroscopy spectroscopy. The stability sequence of the triazole derivatives in CHCl 3 for the metal cations was exhibited a characteristic preference order of extractability to metal ions [Fe(III) > Cu(II) > Pb(II) > Co(II) > Ni(II) > Mn(II) > Zn(II) > Mg(II) > Ca(II)]. The compounds were tested for anti‐microbial activity applying agar diffusion technique for 11 bacteria. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2012