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Synthesis of a chiral stationary phase with poly[styrene‐ b ‐cellulose 2,3‐bis(3,5‐dimethylphenylcarbamate)] by surface‐initiated atom transfer radical polymerization and its chiral resolution efficiency
Author(s) -
Yang JiHoon,
Choi SeongHo
Publication year - 2011
Publication title -
journal of applied polymer science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.575
H-Index - 166
eISSN - 1097-4628
pISSN - 0021-8995
DOI - 10.1002/app.34106
Subject(s) - styrene , cellulose , atom transfer radical polymerization , polymer chemistry , materials science , polymerization , cellulose triacetate , fourier transform infrared spectroscopy , radical polymerization , copolymer , chemistry , organic chemistry , polymer , chemical engineering , engineering
A chiral stationary phase (CSP) with poly[styrene‐ b ‐cellulose 2,3‐bis(3,5‐dimethylphenylcarbamate)] was synthesized by the surface‐initiated atom transfer radical polymerization (SI‐ATRP) of cellulose 2,3‐bis(3,5‐dimethylphenylcarbamate)‐6‐acrylate after the SI‐ATRP of styrene on the surface of silicon dioxide supports in pyridine. The successful preparation of the CSP with poly[styrene‐ b ‐cellulose 2,3‐bis(3,5‐dimethylphenylcarbamate)] was confirmed via Fourier transform infrared spectroscopy, field emission scanning electron microscopy, X‐ray photoelectron spectroscopy, elemental analysis, and thermal analysis. The applicability for the chiral resolution of the CSP with poly[styrene‐ b ‐cellulose 2,3‐bis(3,5‐diphenylcarbamate)] was evaluated with high‐performance liquid chromatography with 10 racemates under various mobile phases of hexane/alcohol, hexane/tetrahydrofuran (THF), and hexane/chloroform. The results show that the CSP with poly[styrene‐ b ‐cellulose 2,3‐bis(3,5‐diphenylcarbamate)] could be used in THF and chloroform as eluents. The chiral resolutions of the commercial Chiracel OD, the CSP with cellulose 2,3‐bis(3,5‐dimethylphenylcarabmate), and the CSP with poly[styrene‐ b ‐cellulose 2,3‐bis(3,5‐dimethylphenylcarbamate)] prepared by SI‐ATRP were examined. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2011