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Synthesis and antimicrobial activity of some cross‐linked copolymers with alkyl chains of various lengths
Author(s) -
Zhang Yuhong,
Li Xiaohong,
Dong Qinzheng,
He Peixin
Publication year - 2010
Publication title -
journal of applied polymer science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.575
H-Index - 166
eISSN - 1097-4628
pISSN - 0021-8995
DOI - 10.1002/app.33382
Subject(s) - alkyl , copolymer , ammonium , antibacterial activity , polymer chemistry , chemistry , monomer , antimicrobial , polymer , acrylamide , nuclear chemistry , organic chemistry , bacteria , biology , genetics
Amphoteric polymer hydrogels were prepared by the copolymerization of three kinds of N , N ′‐dimethyl‐ N ‐alkylmethacryloxylethyl ammoniumbromide (DMAEA) with different lengths of alkyl chains (DMAEA‐RB) ( R ‐ehtyl/hexyl/dodecyl), acrylic acid (AA), and acrylamide (AM). The water content of the AA‐AM‐(DMAEA‐RB) terpolymers decreased with the increasing length of alkyl chains in quaternary ammonium group in the terpolymers and increased with the increasing molar ratio of DMAEA‐RB to 2 mol % and then decreased. Their antibacterial activities against Escherichia coli and Staphylococcus hyicus were investigated by a colony count method. It was found that the copolymer exhibited higher antibacterial activity with increasing chain length of alkyl groups in ammonium groups. For P[AA‐AM‐(DMAEA‐DB)], the DMAEA‐DB content is higher and contact time is longer, its antibacterial activity is better. However, when the contact time and quaternary ammonium content were above 30 min and 2%, respectively, the amount of live cells N ( t ) in a cell suspension increased in the presence of P[AA‐AM‐(DMAEA‐EB)] or P[AA‐AM‐(DMAEA‐HB)]. © 2010 Wiley Periodicals, Inc. J Appl Polym Sci, 2011