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Efficiency and biocompatibility of antimicrobial textile material of broad spectrum activity
Author(s) -
Simović Ljiljana M.,
Škundrić Petar D.,
Kostić Mirjana M.,
Tasić Goran M.,
Kojić Zvezdana Ž.,
Milaković Branko D.,
Medović Adela H.
Publication year - 2010
Publication title -
journal of applied polymer science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.575
H-Index - 166
eISSN - 1097-4628
pISSN - 0021-8995
DOI - 10.1002/app.33235
Subject(s) - biocompatibility , antimicrobial , textile , gentamicin sulfate , viscose , materials science , polymer , nanocellulose , nonwoven fabric , polypropylene , chitosan , in vivo , chemistry , gentamicin , composite material , antibiotics , cellulose , organic chemistry , microbiology and biotechnology , fiber , metallurgy , biochemistry , biology
The subject of this article is to study the behavior of the antimicrobial textile material. The material is in the form of plaster wound dressing which is consisting of a nonwoven textile base containing polypropylene (PP)/viscose, a polymer carrier, and an antimicrobial active substance. The polymer carrier is the polysaccharide D ‐glucosamine (chitosan), and the active antimicrobial substance is antibiotic gentamicin sulfate. The amount of gentamicin sulfate immobilized into the polymer matrix of the polymer carrier was 0.15–0.20 mg/cm 2 or 2.0–2.5% of the mass of the nonwoven textile material. The antimicrobial textile material has been studied in vitro and in vivo conditions through the efficiency of the antimicrobial effects on different kinds of pathogenic microorganisms, as well as the biocompatibility in preclinical research. The results of these experiments indicate that all bioactive textile materials were biocidal in vitro for all pathogenic test organisms. Good biocompatibility, the existence of the correlation between the in vitro and in vivo results, concerning efficiency, qualifies these antimicrobial biomaterials for clinical use. © 2010 Wiley Periodicals, Inc. J Appl Polym Sci, 2011