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Synthesis and characterization of novel lipid functionalized poly(ε‐caprolactone)s
Author(s) -
Oledzka E.,
Kong X.,
Narine S. S.
Publication year - 2010
Publication title -
journal of applied polymer science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.575
H-Index - 166
eISSN - 1097-4628
pISSN - 0021-8995
DOI - 10.1002/app.32898
Subject(s) - caprolactone , lipase , monomer , crystallinity , polymer chemistry , oleic acid , chemistry , polymer , degradation (telecommunications) , enzyme , molecular mass , organic chemistry , polymerization , biochemistry , telecommunications , computer science , crystallography
A series of novel lipid functionalized poly(ε‐caprolactone)s (PCLs) were synthesized through ROP of ε‐caprolactone in the presence of threo ‐9,10‐dihydroxyoctadecanoic acid, synthesized from oleic acid. PCLs with different molecular weights were obtained by controlling the molar ratio of the initiator to the monomer. DSC and XRD analysis indicate that the crystallinity of PCLs decreased when compared to unfunctionalized PCL. The enzymatic degradation study shows that for samples with lower lipid derivatives content, a higher enzymatic degradation rate was observed because the lipase enzymes attack the ester bonds of the polymer; increased lipid content therefore inhibits the action of the lipase enzymes. © 2010 Wiley Periodicals, Inc. J Appl Polym Sci, 2011