Factorial experimental design on synthesis of functional core/shell polymeric nanoparticles via differential microemulsion polymerization

Functionalized core/shell nanoparticles of the co‐polymer of methyl methacrylate (MMA) and glycidyl methacrylate (GMA) could be polymerized by differential microemulsion polymerization, using a small amount of surfactant (the weight ratio of sodium dodecyl sulfate (SDS)/monomer is 1 : 24). The core/shell nanoparticles have a high conversion, high molecular weight, and small particle size (25–30 nm). The statistical analysis indicated that SDS, water, and the interactionbetween SDS and water have a significant positive interaction between the MMA conversion to form the core nanoparticles. For the core‐shell polymer, [GMA], [GMA]*[SDS], and [GMA]* [water] have significant negative effects on conversion; whereas [SDS] and [water], [SDS]*[water] and [GMA]*[SDS]*[water] have positive effects on the conversion to form core/shell nanoparticles. © 2009 Wiley Periodicals, Inc. J Appl Polym Sci, 2010