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Evaluation of water sorption behavior and in vitro blood compatibility of polyvinyl alcohol based magnetic bionanocomposites
Author(s) -
Bajpai A. K.,
Gupta Rashmi
Publication year - 2009
Publication title -
journal of applied polymer science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.575
H-Index - 166
eISSN - 1097-4628
pISSN - 0021-8995
DOI - 10.1002/app.30953
Subject(s) - materials science , polyvinyl alcohol , nanocomposite , biocompatibility , superparamagnetism , sorption , chemical engineering , self healing hydrogels , polymer , magnetic nanoparticles , differential scanning calorimetry , scanning electron microscope , nanoparticle , polymer chemistry , composite material , nanotechnology , chemistry , organic chemistry , adsorption , magnetization , physics , quantum mechanics , magnetic field , engineering , metallurgy , thermodynamics
In recent past magnetic bionanocomposites have shown potential in biomedical applications mainly due to their superparamagnetic and biocompatible nature. They have also established themselves as a promising class of hybrid organic–inorganic materials derived from polymers and organic/inorganic fillers. In this study biocompatible nanocomposites were prepared by in situ synthesis of magnetic nanoparticles within the polyvinyl alcohol‐grafted‐polymethyl methacrylate hydrogels and characterized by techniques such as FT‐IR, scanning electron microscopy, transmission electron microscopy, X‐ray diffraction, and differential scanning calorimetry. The bionanocomposites were evaluated for water sorption behavior and in vitro biocompatibility by performing thrombus formation and hemolysis tests. The influence of chemical composition of the grafted hydrogel was investigated on water sorption behavior and in vitro blood compatibility of magnetic bionanocomposites. © 2009 Wiley Periodicals, Inc. J Appl Polym Sci, 2009