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Synthesis and evaluation of chitosan‐vitamin C complexes
Author(s) -
Xiaolin Tian,
Dafeng Tian,
Zhongyan Wang,
Fengkui Mo
Publication year - 2009
Publication title -
journal of applied polymer science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.575
H-Index - 166
eISSN - 1097-4628
pISSN - 0021-8995
DOI - 10.1002/app.30918
Subject(s) - chitosan , distilled water , solubility , polymer , nuclear chemistry , fourier transform infrared spectroscopy , chemistry , polysaccharide , biocompatible material , polymer chemistry , organic chemistry , chemical engineering , chromatography , medicine , engineering , biomedical engineering
Chitosan (CS) is a biocompatible, biodegradable, and nontoxic polysaccharide polymer. It dissolves in water only if the pH is lower than 6.5. To extend its range of application, many water‐soluble derivatives have, therefore, been prepared. In this research, chitosan‐vitamin C complexes (CSVC) were synthesized and characterized with FTIR, DSC, and 1 H‐NMR. The solubility of CSVC in distilled water was greatly improved. The •O 2 ‐ scavenging activity of CSVC was compared with CS and vitamin C (VC) by measuring the auto‐oxidation rate of pyrogallic acid. Results showed that the scavenging activity on •O 2 − by CSVC was stronger than that by CS. © 2009 Wiley Periodicals, Inc. J Appl Polym Sci, 2009