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Synthesis of highly efficient D‐naproxen imprinted polymer and investigation of their specific performance
Author(s) -
Zhang Zhiliang,
Wang Bing
Publication year - 2009
Publication title -
journal of applied polymer science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.575
H-Index - 166
eISSN - 1097-4628
pISSN - 0021-8995
DOI - 10.1002/app.30048
Subject(s) - polymer , naproxen , materials science , molecular imprinting , adsorption , chemical engineering , monomer , solvent , molecularly imprinted polymer , molecule , polymer chemistry , selectivity , organic chemistry , chemistry , catalysis , medicine , alternative medicine , pathology , engineering , composite material
D‐naproxen was selected as the imprinted molecule. An original ultraviolet spectrum analysis method based on proof of solvent effects was designed to verify the realization of the noncovalent self‐assembly between naproxen and functional monomers under the influence of the solvents with different nature. The facts proved that it is a more scientific way to effectively implement the pre‐selection of functional monomer. Then, a series of molecular imprinted polymers (MIPs) were synthesized by different ratios of raw materials. These products were detected by infrared spectroscopy as well as adsorption experimentation to analyze their structure and performance. Meanwhile, the transmission electron microscopy (TEM) was first used to observe the morphology of MIPs, by which the pore‐forming mechanism and the effect of the solvent (porogen) were investigated. The MIPs with morphology of different structure were also tested in the adsorption kinetics experiments to testify the influence of morphology factors on the materials' adsorption properties. Through the evaluation of the imprinting efficiency, the best condition accessing to the preparation of highly efficient D‐naproxen imprinted polymer was obtained. The apparent imprinting efficiency of the ultimate product was as high as 90.39%. © 2009 Wiley Periodicals, Inc. J Appl Polym Sci, 2009