Premium
Cyclodextrin‐anionic polysaccharide hydrogels: Synthesis, characterization, and interaction with some organic molecules (water pollutants, drugs, proteins)
Author(s) -
Mocanu G.,
Mihai D.,
LeCerf D.,
Picton L.,
Moscovici M.
Publication year - 2009
Publication title -
journal of applied polymer science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.575
H-Index - 166
eISSN - 1097-4628
pISSN - 0021-8995
DOI - 10.1002/app.29580
Subject(s) - self healing hydrogels , chemistry , cyclodextrin , polyelectrolyte , reagent , polysaccharide , polymer chemistry , organic chemistry , grafting , bifunctional , hydrolysis , carboxymethyl cellulose , pullulan , chemical engineering , polymer , sodium , engineering , catalysis
Abstract Hydrogel microparticles have been prepared through cocrosslinking of cyclodextrin and of anionic carboxymethyl or sulfopropyl pullulan with a new bifunctional reagent: 3‐(glycidoxypropyl)trimethoxysilane. This reagent forms crosslinking both through grafting with the epoxy end on the OH polysaccharide and through hydrolysis and condensation of the methoxy silane groups from the other end. Samples of cyclodextrin/anionic polysaccharides with various amounts of crosslinking agent were prepared. Characterization of the hydrogel microparticles considered the water swelling behavior, porosity measurements, retention of biologically active substances, which can occur by their inclusion in cyclodextrin inner cavities and in the pores of hydrogels, as well as through the electrostatic forces toward anionic polyelectrolyte charges. Their improved retention of various organic molecules as water pollutants, drugs, enzymes, recommend them as chromatographic supports, supports for the separation/immobilization of enzymes or for controlled release systems. © 2009 Wiley Periodicals, Inc. J Appl Polym Sci, 2009