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Using polystyrene‐ co ‐maleic acid for molecularly imprinted membranes prepared in supercritical carbon dioxide
Author(s) -
Kobayashi Takaomi,
Leong Su Si,
Zhang Quanqiu
Publication year - 2008
Publication title -
journal of applied polymer science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.575
H-Index - 166
eISSN - 1097-4628
pISSN - 0021-8995
DOI - 10.1002/app.27734
Subject(s) - membrane , supercritical carbon dioxide , supercritical fluid , polystyrene , copolymer , polymer chemistry , materials science , hydrogen bond , styrene , molecular imprinting , molecularly imprinted polymer , thymine , polymer , chemical engineering , selectivity , chemistry , organic chemistry , catalysis , molecule , dna , biochemistry , composite material , engineering
Abstract Supercritical CO 2 (ScCO 2 ) has been used to prepare molecularly imprinted polymers of poly(styrene‐ co ‐maleic acid) (PSMA) for targeted uracil (URA). The condition of ScCO 2 was on 16 MPa between 35 and 50°C. The resultant imprinted membranes prepared at 35 and 50°C bound URA with 9.2 ± 0.10 and 12.6 ± 0.06 μmol g −1 , respectively. Competitive binding studies were undertaken in binary substrate solution containing each of URA/DMURA, URA/Thymine, and URA/Cytosine with 2 μ M . The URA imprinted membrane showed high separation factor (α) with 17 for both URA/DMURA and URA/Thymine and for URA/Cytosine, α = 13. Results strongly suggested that the URA imprinted membrane had effective selectivity hydrogen bonding to separately bind in the binary components to the template. Effect of organic solvents on the URA imprinting in ScCO 2 was also studied, in addition to comparison of properties with those obtained in both ScCO 2 and water. Evidence presented that ScCO 2 medium was effective to prepare the URA imprinted membrane. We discussed that ScCO 2 fluid was efficient to fix the shape of URA template into the PSMA membrane through hydrogen bonding. © 2008 Wiley Periodicals, Inc. J Appl Polym Sci, 2008