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Preparation and characterization of HAP/carboxymethyl chitosan nanocomposites
Author(s) -
Sreedhar B.,
Aparna Y.,
Sairam M.,
Hebalkar Neha
Publication year - 2007
Publication title -
journal of applied polymer science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.575
H-Index - 166
eISSN - 1097-4628
pISSN - 0021-8995
DOI - 10.1002/app.26140
Subject(s) - nanocomposite , x ray photoelectron spectroscopy , fourier transform infrared spectroscopy , materials science , coprecipitation , thermogravimetry , chitosan , thermal stability , scanning electron microscope , transmission electron microscopy , nuclear chemistry , crystallite , chemical engineering , nanotechnology , composite material , chemistry , engineering , metallurgy
Nanocomposites of modified chitosan, carboxymethyl chitosan (CMCh) with hydroxyapatite (HAP) have been prepared by coprecipitation technique. Totally three nanocomposites containing 80/20, 50/50, and 20/80 of HAP/CMCh have been prepared and were characterized by using transmission electron microscopy (TEM), X‐ray diffraction (XRD), fourier transformed infrared spectroscopy (FTIR), X‐ray photoelectron spectroscopy (XPS), thermogravimetry (TG), and scanning electron microscopy (SEM). Modified chitosan, CMCh, which is water soluble can be used for drug delivery application. TEM micrographs of the nanocomposites revealed the formation of small HAP crystallites of about 230 nm in length and 30 nm in width that are aggregated to form elliptical shapes or morphology. TGA thermograms showed that the thermal stability of the CMCh increased with incorporation of HAP. FTIR, XRD, and XPS analysis of CMCh/HAP nanocomposites showed the peaks corresponding to CMCh as well as HAP and confirm the formation of HAP/CMCh nanocomposites. © 2007 Wiley Periodicals, Inc. J Appl Polym Sci 2007