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Preparation of poly(9‐aminoacridine)‐modified electrode and its application in the determination of dopamine and ascorbic acid simultaneously
Author(s) -
Fang Bin,
Liu Hongying,
wang Guangfeng,
Zhou Yunyou,
Jiao Shoufeng,
Gao Xianguo
Publication year - 2007
Publication title -
journal of applied polymer science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.575
H-Index - 166
eISSN - 1097-4628
pISSN - 0021-8995
DOI - 10.1002/app.25995
Subject(s) - ascorbic acid , electrode , differential pulse voltammetry , detection limit , electrochemistry , materials science , analytical chemistry (journal) , cyclic voltammetry , buffer solution , anode , chemistry , nuclear chemistry , chromatography , food science
A novel modified electrode was fabricated with 9‐aminoacridine by electropolymerization in the phosphate buffer solution (PBS) (pH 7.4) and was characterized by cyclic voltammetry (CV). The modified electrode showed excellent electrocatalytic effect and high stability toward the electrochemical oxidation of dopamine (DA) and ascorbic acid (AA). Also, it showed a high stability for the determination of DA and AA simultaneously. Well‐separated voltammetric peaks were observed for DA and AA on the modified electrode. The separation of two anodic peaks was 170 mV, which was large enough to eliminate the interference of AA and determine DA. The differential pulse voltammograms (DPV) were used for the measurement of DA by means of the poly(9‐aminoacridine)‐modified electrode in PBS at pH 7.4. A linear response toDA was observed in the concentration range from 1.5 × 10 −6 to 3.5 × 10 −3 mol L −1 with a correlation coefficient of 0.9998 and a detection limit ( S / N = 3) of 1.0 × 10 −7 mol L −1 . The proposed method was used to determine DA in DA‐hydrochloride injection and showed excellent sensitivity and recovery. The ease of fabrication, good reproducibility, high stability, and low cost of the modified electrode are the promising features of the proposed sensor. © 2007 Wiley Periodicals, Inc. J Appl Polym Sci 104: 3864–3870, 2007