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Preparation and characterization of macroporous poly(2‐hydroxyethyl methacrylate)‐based biomaterials: Water sorption property and in vitro blood compatibility
Author(s) -
Bajpai A. K.,
Kankane Sanjana
Publication year - 2007
Publication title -
journal of applied polymer science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.575
H-Index - 166
eISSN - 1097-4628
pISSN - 0021-8995
DOI - 10.1002/app.25580
Subject(s) - differential scanning calorimetry , 2 hydroxyethyl methacrylate , interpenetrating polymer network , materials science , methacrylate , sorption , glutaraldehyde , polymer chemistry , swelling , chemical engineering , polymer , fourier transform infrared spectroscopy , (hydroxyethyl)methacrylate , adsorption , nuclear chemistry , chemistry , composite material , polymerization , organic chemistry , physics , engineering , thermodynamics
A semi‐interpenetrating polymer network (IPN) comprising gelatin and poly(2‐hydroxyethyl methacrylate‐ co ‐acrylamide) was prepared and characterized by FTIR, environmental scanning electron microscopy (ESEM) and differential scanning calorimetry (DSC) techniques. The water sorption potential of the prepared semi‐IPNs was investigated for varying chemical architecture of the IPN, and experimental conditions such as pH, temperature and ionic strength of the swelling media. The semi‐IPNs were also judged for in vitro blood compatibility by performing blood clot, percent hemolysis, protein adsorption and platelet adhesion tests. © 2007 Wiley Periodicals, Inc. J Appl Polym Sci 104: 1559–1571, 2007