Premium
Radiation synthesis of interpenetrating polymer networks based on N ‐vinyl pyrrolidone – acrylic acid copolymer and gelatin. I. Swelling, morphology, and thermal characterization for biomedical applications
Author(s) -
Singh Dipti,
Choudhary Veena,
Koul Veena
Publication year - 2007
Publication title -
journal of applied polymer science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.575
H-Index - 166
eISSN - 1097-4628
pISSN - 0021-8995
DOI - 10.1002/app.24974
Subject(s) - gelatin , copolymer , acrylic acid , swelling , polymer chemistry , interpenetrating polymer network , materials science , self healing hydrogels , glutaraldehyde , polymer , 2 pyrrolidone , chemical engineering , nuclear chemistry , chemistry , composite material , organic chemistry , engineering
Interpenetrating polymer networks (IPNs) based on N ‐vinyl pyrrolidone (NVP) : gelatin (Ge), and a copolymer of NVP – acrylic acid (AA) : gelatin (Ge) were prepared using N‐N′ methylenebisacrylamide (BIS) (0.5, 1% w/w) and glutaraldehyde (GLU) (0.5% v/v) as crosslinkers, respectively, by gamma irradiation technique. GLU was incorporated after irradiation to crosslink the gelatin chains, whereas BIS was placed in the respective solutions before irradiation. Several samples were prepared by varying the composition of gelatin to NVP or by changing the ratio of NVP : AA in preparing IPNs. The swelling behavior of the hydrogels was investigated as a function of variable doses, crosslinker (BIS) concentration, copolymer composition (NVP : AA ratio) or Ge : NVP ratio and pH of the immersion medium (3, 7.4, and 11). As expected, the swelling ratio increased with increasing acrylic acid content and decreased with increasing BIS content. No definite trend in the swelling behavior was observed as a function of dose. The interpenetration of the polymeric chains was established by morphological and thermal characterization. Scanning electron microscopy of IPNs showed a hybrid of coral and honeycomb structures as compared with the crosslinked polymers based on Ge and NVP (G x and PVP x ). © 2007 Wiley Periodicals, Inc. J Appl Polym Sci 104: 1456–1463, 2007