Premium
Effect of hydrotalcite on the physical properties and drug‐release behavior of nanocomposite hydrogels based on poly[acrylic acid‐ co ‐poly(ethylene glycol) methyl ether acrylate] gels
Author(s) -
Lee WenFu,
Chen YungChu
Publication year - 2004
Publication title -
journal of applied polymer science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.575
H-Index - 166
eISSN - 1097-4628
pISSN - 0021-8995
DOI - 10.1002/app.20936
Subject(s) - materials science , self healing hydrogels , nanocomposite , ethylene glycol , acrylate , acrylic acid , polymer chemistry , bioadhesive , swelling , exfoliation joint , adhesive , chemical engineering , polymer , ether , copolymer , composite material , organic chemistry , chemistry , nanotechnology , graphene , layer (electronics) , engineering
Abstract A series of nanocomposite hydrogels used for bioadhesive were prepared from acrylic acid, poly(ethylene glycol) methyl ether acrylate, and intercalated hydrotalcite (HT) by photopolymerization. The microstructures of the intercalated HT and sample gels were identified by X‐ray diffraction (XRD). The results showed that the swelling ratio for these nanocomposite hydrogels increased with an increase in HT, but the gel strength and adhesive force for these gels decreased with an increase in HT. The XRD results indicated that the exfoliation of intercalated HT was achieved in the xerogels and swollen gels. Finally, the drug‐release behaviors for these gels were also examined. © 2004 Wiley Periodicals, Inc. J Appl Polym Sci 94: 692–699, 2004