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Properties of biomedical pressure‐sensitive adhesive copolymer films with pendant monosaccharides
Author(s) -
Miyata Takashi,
Morizane Mayumi,
Nakamae Katsuhiko,
Okumura Masakazu,
Kinomura Keisuke
Publication year - 1995
Publication title -
journal of applied polymer science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.575
H-Index - 166
eISSN - 1097-4628
pISSN - 0021-8995
DOI - 10.1002/app.1995.070561212
Subject(s) - copolymer , adhesive , methacrylate , materials science , polymer chemistry , pressure sensitive , transdermal , acrylate , butyl acrylate , chemical engineering , composite material , polymer , medicine , layer (electronics) , pharmacology , engineering
Glucosyloxyethyl methacrylate (GEMA) was copolymerized with butyl acrylate (BA) for the preparation of a biomedical pressure‐sensitive adhesive with pendant monosaccharides, for possible use in medical applications. The measurements of 180° peel strength, ball tack, and holding power for the GEMA–BA copolymer films revealed that the film at the GEMA content of 5 mol % has excellent pressure‐sensitive adhesive properties. Protein adsorption onto the GEMA–BA copolymer film hardly occurred due to very low interfacial free energy between its surface and water. Release profiles of vitamin B 12 from the GEMA–BA copolymer film suggests that it is useful as a material for a transdermal therapeutic system. © 1995 John Wiley & Sons, Inc.