Properties of biomedical pressure‐sensitive adhesive copolymer films with pendant monosaccharides | Zendy

Miyata Takashi | Zendy; Morizane Mayumi | Zendy; Nakamae Katsuhiko | Zendy; Okumura Masakazu | Zendy; Kinomura Keisuke | Zendy

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Properties of biomedical pressure‐sensitive adhesive copolymer films with pendant monosaccharides

Author(s) -

Miyata Takashi,

Morizane Mayumi,

Nakamae Katsuhiko,

Okumura Masakazu,

Kinomura Keisuke

Publication year - 1995

Publication title -

journal of applied polymer science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.575

H-Index - 166

eISSN - 1097-4628

pISSN - 0021-8995

DOI - 10.1002/app.1995.070561212

Subject(s) - copolymer , adhesive , methacrylate , materials science , polymer chemistry , pressure sensitive , transdermal , acrylate , butyl acrylate , chemical engineering , composite material , polymer , medicine , layer (electronics) , pharmacology , engineering

Glucosyloxyethyl methacrylate (GEMA) was copolymerized with butyl acrylate (BA) for the preparation of a biomedical pressure‐sensitive adhesive with pendant monosaccharides, for possible use in medical applications. The measurements of 180° peel strength, ball tack, and holding power for the GEMA–BA copolymer films revealed that the film at the GEMA content of 5 mol % has excellent pressure‐sensitive adhesive properties. Protein adsorption onto the GEMA–BA copolymer film hardly occurred due to very low interfacial free energy between its surface and water. Release profiles of vitamin B 12 from the GEMA–BA copolymer film suggests that it is useful as a material for a transdermal therapeutic system. © 1995 John Wiley & Sons, Inc.

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