Premium
Polymeric phosphonium salts as a novel class of cationic biocides. VIII. Synergistic effect on antibacterial activity of polymeric phosphonium and ammonium salts
Author(s) -
Kanazawa Akihiko,
Ikeda Tomiki,
Endo Takeshi
Publication year - 1994
Publication title -
journal of applied polymer science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.575
H-Index - 166
eISSN - 1097-4628
pISSN - 0021-8995
DOI - 10.1002/app.1994.070530911
Subject(s) - phosphonium , cationic polymerization , monomer , antibacterial activity , ammonium chloride , chemistry , ammonium , copolymer , phosphonium salt , polymer chemistry , biocide , polymer , chloride , salt (chemistry) , organic chemistry , bacteria , biology , genetics
Abstract Two types of homopolymers {poly[tributyl(4‐vinylbenzyl)phosphonium chloride] and poly[tributyl(4‐vinylbenzyl)ammonium chloride]} and copolymers, in which the compositional ratio of the phosphonium monomer to the ammonium monomer was altered, were prepared. The antibacterial activities of both the mixtures of the homopolymers in which the mixing ratio was altered and the copolymers containing positively charged phosphorus and nitrogen atoms in a single polymer chain were explored by the viable cell counting method in sterile distilled water. In the mixed system, a significant finding was the presence of an optimal mixing ratio for the antibacterial activity. The mixtures of polymeric phosphonium salt and polymeric ammonium salt clearly showed the synergistic effect on the antibacterial activity. On the other hand, the antibacterial activity of the copolymers with different cationic parts increased monotonously with increasing the phosphonium monomer units in the polymers, namely, the incorporation of two types of active moieties into a single molecule seems to be unfavorable for synergism on the antibacterial activity. © 1994 John Wiley & Sons, Inc.