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Reverse osmosis separation of amino acids in aqueous solutions using porous cellulose acetate membranes
Author(s) -
Matsuura Takeshi,
Sourirajan S.
Publication year - 1974
Publication title -
journal of applied polymer science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.575
H-Index - 166
eISSN - 1097-4628
pISSN - 0021-8995
DOI - 10.1002/app.1974.070181209
Subject(s) - aqueous solution , membrane , steric effects , chemistry , ionic bonding , semipermeable membrane , amino acid , cellulose triacetate , cellulose acetate , reverse osmosis , cellulose , molecule , ionic strength , chromatography , inorganic chemistry , organic chemistry , ion , biochemistry
Polar and steric effects together govern the reverse osmosis separation of amino acids in single‐solute aqueous solution systems. The solute transport parameter for the completely ionized aliphatic amino acids (with no additional polar groups other than one NH 2 and one COOH) in the p K 1 range of 4.03 to 1.71 can be represented as a function of p K 1 and the steric parameter Σ E s . The latter parameter has a relatively greater influence with respect to the separation of zwitter ions. The effect of the polar parameter p K 1 on solute separation increases with increase in the concentration of the ionic species R + (or decrease in the concentration of the ionic species R − ) in the feed solution. The effect of the presence of additional polar groups in the amino acid molecule is to increase its basicity. Experiments with p ‐aminobenzoic acid solutions indicate that the undissociated acid is preferentially sorbed at the membrane–solution interface. With respect to both aliphatic and aromatic amino acid ions, solute separation is in the order R − > R ± > R + for the cellulose acetate membrane material studied.