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Crosslinked poly(acryloylmorpholines) as matrices for gel permeation chromatography
Author(s) -
Epton R.,
Holloway C.,
McLaren J. V.
Publication year - 1974
Publication title -
journal of applied polymer science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.575
H-Index - 166
eISSN - 1097-4628
pISSN - 0021-8995
DOI - 10.1002/app.1974.070180116
Subject(s) - gel permeation chromatography , tetrahydrofuran , size exclusion chromatography , polystyrene , chloroform , molar mass distribution , polymer chemistry , molar mass , swelling , chromatography , permeation , aqueous solution , chemistry , polyethylene , polymerization , materials science , membrane , polymer , organic chemistry , solvent , composite material , biochemistry , enzyme
Crosslinked poly(acryloylmorpholines) have been prepared in bead form by suspension polymerization of N‐acryloylmorpholine and N,N′‐methylenediacrylamide, respective molar ratios 10/1, in aqueous solution dispersed in liquid paraffin. The swelling properties of beads of two porosities, designated Enzacryl Gel K1 and Enzacryl Gel K2, were measured in a range of common solvents. Gels derived by swelling in both chloroform and tetrahydrofuran were evaluated as column packings for gel permeation chromatography. For Enzacryl Gel K1 and polystyrene solutes, molecular weight exclusion limits of approximately 4 × 10 3 and 6 × 10 2 were observed in chloroform and tetrahydrofuran, respectively. In the case of Enzacryl Gel K2, the corresponding exclusion limits were 10 4 and 5 × 10 3 . Molecular weight fractionation ranges for both polystyrenes and polyethylene glycols are discussed in terms of gel structure.