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Theoretical analysis and critique of the chromatographic separation of macromolecules using porous adsorbents
Author(s) -
White James L.,
Kingry Gary W.
Publication year - 1970
Publication title -
journal of applied polymer science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.575
H-Index - 166
eISSN - 1097-4628
pISSN - 0021-8995
DOI - 10.1002/app.1970.070141106
Subject(s) - adsorption , macromolecule , chromatography , fractionation , chromatographic separation , porosity , chemistry , size exclusion chromatography , molecule , separation method , chemical engineering , separation (statistics) , materials science , organic chemistry , high performance liquid chromatography , computer science , biochemistry , machine learning , engineering , enzyme
A theoretical analysis of the separation of a mixture of macromolecules by a chromatographic column packed with porous adsorbents is given. Fractionation may take place by either exclusion of large molecules from the pores in the column packing or by selective adsorption. A model for packing structure is developed which is used as the basis of a theory of chromatographic separation.
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