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Radiation chemical studies of protein reactions: Effect of amino acids on optical rotation
Author(s) -
Nisizawa Mizuho
Publication year - 1969
Publication title -
journal of applied polymer science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.575
H-Index - 166
eISSN - 1097-4628
pISSN - 0021-8995
DOI - 10.1002/app.1969.070131103
Subject(s) - optical rotation , amino acid , inosine , aspartic acid , chemistry , guanosine , specific rotation , arginine , molecule , glutamic acid , sodium glutamate , inosine monophosphate , stereochemistry , organic chemistry , biochemistry , enzyme , nucleotide , raw material , gene
Monosodium 1‐glutamate, disodium inosine‐5′‐monophosphate, disodium guanosine‐5′‐monophosphate, calcium d ‐pantothanate, 1‐arginine, and 1‐aspartic acid were found to protect the changes in the internal relationships of the atoms in the protein molecule from radiation damage. The behavior of the optical rotation was determined. The empirical equation for the protective effect is given by [α] f = b − a log X, where [α] f is the final specific rotation of the solution, X is the concentration of the amino acids, and a and b are adjustable constants.