Premium
Radiation chemical studies of protein reactions: Radiation dose and optical rotation
Author(s) -
Nisizawa Mizuho
Publication year - 1969
Publication title -
journal of applied polymer science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.575
H-Index - 166
eISSN - 1097-4628
pISSN - 0021-8995
DOI - 10.1002/app.1969.070131102
Subject(s) - rotation (mathematics) , optical rotation , radiation , irradiation , molecule , cobalt 60 , physics , chemistry , position (finance) , equation of state , chemical reaction , materials science , thermodynamics , optics , quantum mechanics , organic chemistry , mathematics , finance , geometry , economics
When protein was irradiated by gamma rays from a cobalt 60 sources, an activated state on the position of the groups in the vicinity of the asymmetric carbon atoms in the protein molecule was caused. An empirical equation for the change in optical rotation was obtained, and the phenomena were explained on the basis of the molecular mechanism. The general equation for the change in optical rotation is given by [α] = ( b + a log R) (1 − e − kt ), where [α] is the specific rotation of the solution, R is the gamma radiation dose, t is time, and a , b , and k are adjustable constants.