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Antimicrobial activity of a monomer and its polymer based on quinolone
Author(s) -
Moon WoongSig,
Chul Kim Jae,
Chung KyooHyun,
Park EunSoo,
Kim MalNam,
Yoon JinSan
Publication year - 2003
Publication title -
journal of applied polymer science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.575
H-Index - 166
eISSN - 1097-4628
pISSN - 0021-8995
DOI - 10.1002/app.12813
Subject(s) - monomer , polycaprolactone , polymer chemistry , azobisisobutyronitrile , low density polyethylene , materials science , polymer , methyl methacrylate , polypropylene , methacrylate , moiety , polymerization , chemistry , organic chemistry , composite material
An acryl monomer containing the quinolone moiety was synthesized and then polymerized with azobisisobutyronitrile in a dimethylformamide solution. The resulting polymer as well as the corresponding monomer exhibited an excellent antibacterial activity. The poly(acrylated quinolone) (PQ) was compounded with other ordinary synthetic polymers such as low‐density polyethylene (LDPE), poly(butylene succinate) (PBS), poly(methyl methacrylate) (PMMA), maleated polypropylene (PPMA), and polycaprolactone (PCL). The polymer blends reduced the viable cell number significantly on contact during the shake flask test even when the PQ content was as low as 1 wt %. © 2003 Wiley Periodicals, Inc. J Appl Polym Sci 90: 1797–1801, 2003