z-logo
Premium
A novel amphoteric, pH‐sensitive, biodegradable poly[chitosan‐ g ‐( L ‐lactic‐ co ‐citric) acid] hydrogel
Author(s) -
Yao Fanglian,
Chen Wei,
Liu Chang,
De Yao Kang
Publication year - 2003
Publication title -
journal of applied polymer science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.575
H-Index - 166
eISSN - 1097-4628
pISSN - 0021-8995
DOI - 10.1002/app.12567
Subject(s) - swelling , chitosan , citric acid , lactic acid , fourier transform infrared spectroscopy , polymer chemistry , nuclear chemistry , aqueous solution , kinetics , chemistry , self healing hydrogels , materials science , chemical engineering , organic chemistry , composite material , physics , quantum mechanics , biology , bacteria , engineering , genetics
The novel amphoteric, pH‐sensitive, biodegradable poly([chitosan‐ g ‐( L ‐lactic‐ co ‐citric) acid]) hydrogel (CLC) was synthesized through the reaction of chitosan (CS) with poly( L ‐lactic‐ co ‐citric acid) (PLCA). The structure of CLC was characterized by Fourier transform infrared spectroscopy, elemental analysis, and wide‐angle X‐ray diffraction measurement. The degree of substitution of CS amino groups was evaluated from salicylaldehyde analysis. The swelling behavior of CLC film in an aqueous solution with various pHs and the apparent swelling kinetics were studied. The swelling mechanisms of CLC film in acidic and alkaline mediums are discussed. The results showed that CLC hydrogel had a higher degree of swelling in the pH range of 4 > pH > 8 and that the swelling rate order in different buffers was neutral > acidic > basic mediums. © 2003 Wiley Periodicals, Inc. J Appl Polym Sci 89: 3850–3854, 2003

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here