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Water‐soluble cationic polymers and their polymer–metal complexes with biocidal activity: A genotoxicity study
Author(s) -
Rivas Bernabé L.,
Pereira Eduardo D.,
Mondaca María A.,
Rivas Rodrigo J.,
Saavedra Margarita A.
Publication year - 2002
Publication title -
journal of applied polymer science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.575
H-Index - 166
eISSN - 1097-4628
pISSN - 0021-8995
DOI - 10.1002/app.11399
Subject(s) - cationic polymerization , genotoxicity , chemistry , polyelectrolyte , polymer , nuclear chemistry , silver nitrate , ammonium , metal ions in aqueous solution , metal , macromolecule , staphylococcus aureus , polymer chemistry , bacteria , organic chemistry , biochemistry , biology , toxicity , genetics
Water‐soluble polyelectrolytes containing ammonium and sulfonic groups, their polymer–Ag(I) complexes, and silver nitrate were investigated as bactericidal compounds for Staphylococcus aureus (Collection No. ATCC 28922) and Escherichia coli (Collection No. 6538P) according to the National Committee for Clinical Laboratory Standards (NCCL) method. All the compounds, except Ag(I), showed bactericidal activity only for S. aureus . Ag(I) showed high bactericidal activity for both bacteria. No important effect of the molecular weight or macromolecular size on the maximum bactericidal concentration value was observed. The genotoxicity was studied using the rec assay. None of the macromolecular compounds showed genotoxicity, except silver ions, whose value was borderline. © 2002 Wiley Periodicals, Inc. J Appl Polym Sci 87: 452–457, 2003