Premium
Surface modification of poly‐ L ‐lactide by photografting of hydrophilic polymers towards improving its hydrophilicity
Author(s) -
Ma Zuwei,
Gao Changyou,
Yuan Jun,
Ji Jian,
Gong Yihong,
Shen Jiacong
Publication year - 2002
Publication title -
journal of applied polymer science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.575
H-Index - 166
eISSN - 1097-4628
pISSN - 0021-8995
DOI - 10.1002/app.10803
Subject(s) - photografting , materials science , contact angle , polymer chemistry , surface modification , membrane , polymer , copolymer , chemical engineering , grafting , biomaterial , methacrylate , polymerization , wetting , attenuated total reflection , fourier transform infrared spectroscopy , chemistry , composite material , nanotechnology , biochemistry , engineering
Poly‐ L ‐lactide (PLLA) has been used to prepare scaffolds to guide tissue regeneration in tissue engineering research. However, one of the limitations to the use of PLLA as an ideal biomaterial is its high hydrophobicity. To improve the hydrophilicity of PLLA, hydrophilic polymers were grafted onto PLLA membrane surfaces through the combination of photooxidization in hydrogen peroxide and subsequent ultraviolet (UV)‐induced grafting copolymerization in the monomer solution. Three kinds of modified PLLA membranes (i.e., PLLA‐g‐polyhydroxyethyl methacrylate, PLLA‐g‐polyacrylamide, and PLLA‐g‐polymethacrylic acid) were obtained, resulting in the more wettable PLLA membranes. The occurrence of the grafting polymerization was confirmed by attenuated total reflectance infrared spectroscopy (ATR‐IR) and X‐ray photoelectron spectroscopy (XPS) analysis. Surface morphology of the modified PLLA membranes was studied by scan electronic microscopy (SEM). © 2002 Wiley Periodicals, Inc. J Appl Polym Sci 85: 2163–2171, 2002