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Kinetics of continuous production of β ‐carotene in an airlift bioreactor
Author(s) -
Taavoni Shoeib,
Habibi Alireza,
Varmira Kambiz,
Alipour Sajad
Publication year - 2017
Publication title -
asia‐pacific journal of chemical engineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.348
H-Index - 35
eISSN - 1932-2143
pISSN - 1932-2135
DOI - 10.1002/apj.2160
Subject(s) - bioreactor , airlift , chemostat , dilution , chromatography , chemistry , food science , biochemistry , biology , bacteria , organic chemistry , physics , genetics , thermodynamics
The focus in the present work was on the continuous β‐carotene production from free fatty acids supplied by the soap stock as a sole carbon source for Rhodotorula rubra cells in an airlift bioreactor. The effects of dilution rate on the cell growth and β‐carotene production were studied by both freely suspended‐ and immobilized‐cell systems in the chemostat operations. The results showed that the immobilization of the cell on natural sponge of loofah significantly increased the optimum and maximum dilution rates from 0.0375 to 0.05 hr −1 and 0.055 to 0.150 hr −1 , respectively. The immobilization process has practical role in balancing of cell proliferation in the matrix and wash out the grown cells containing β‐carotene from the bioreactor where β ‐ carotene productivity was enhanced from 5.4 to 23.4 mg L −1 hr −1 using the immobilized cell technology.