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Binding kinetics of magnetic nanoparticles on latex beads studied by magnetorelaxometry
Author(s) -
Eberbeck D.,
Bergemann Ch.,
Hartwig S.,
Steinhoff U.,
Trahms L.
Publication year - 2004
Publication title -
applied organometallic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 71
eISSN - 1099-0739
pISSN - 0268-2605
DOI - 10.1002/aoc.758
Subject(s) - chemistry , kinetics , magnetic relaxation , magnetic nanoparticles , relaxation (psychology) , nanoparticle , receptor–ligand kinetics , squid , macromolecule , spheres , chemical engineering , nanotechnology , polymer chemistry , magnetization , magnetic field , materials science , biochemistry , psychology , social psychology , ecology , physics , receptor , quantum mechanics , astronomy , engineering , biology
A system of magnetic nanoparticles (MNPs) and modified latex spheres was used serving as a model for studying binding reactions. The binding of MNPs on latex is estimated by the change of the magnetic relaxation properties of the MNP measured by a SQUID‐based magnetorelaxometry measurement system. By fitting of subsequently recorded relaxation curves, the kinetics of the binding reactions, i.e. the evolution of the fraction of bound MNPs, was extracted. The signal of bound MNPs scales linearly with the concentration of latex beads. For low latex concentrations the kinetics are described by a simple aggregation model, providing information about the density and probability of bindings to the target surface. Copyright © 2004 John Wiley & Sons, Ltd.