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A simple and practical protocol for the palladium‐catalyzed cross‐coupling of boronic acids with methyl iodide
Author(s) -
Gooßen Lukas J.
Publication year - 2004
Publication title -
applied organometallic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 71
eISSN - 1099-0739
pISSN - 0268-2605
DOI - 10.1002/aoc.746
Subject(s) - chemistry , palladium , catalysis , iodide , methyl iodide , organic chemistry , coupling (piping) , combinatorial chemistry , mechanical engineering , engineering
A combination of palladium acetate and tri‐1‐naphthylphosphine was found to be a highly efficient catalyst system for the cross‐coupling of arylboronic acids with methyl iodide at room temperature. The new process allows for a convenient introduction of methyl groups into various functionalized arenes under mild conditions. Copyright © 2004 John Wiley & Sons, Ltd.
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