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Palladium‐catalyzed cross‐coupling reactions of coumarin derivatives: An overview
Author(s) -
Kanchana U.S.,
Diana Elizabeth J.,
Mathew Thomas V.,
Anilkumar Gopinathan
Publication year - 2020
Publication title -
applied organometallic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 71
eISSN - 1099-0739
pISSN - 0268-2605
DOI - 10.1002/aoc.5983
Subject(s) - chemistry , stille reaction , palladium , catalysis , coupling reaction , coumarin , combinatorial chemistry , organic chemistry , heck reaction , suzuki reaction , organic synthesis
Coumarins are omnipresent in several plants and exhibit a plethora of pharmacological properties, making them an important scaffold in organic synthesis. Naturally, the chemistry of this motif has attracted ever‐increasing attention, among which palladium‐catalyzed coupling reactions are the most prevalent one. Numerous useful, easy, and concise syntheses and reactions have been achieved using palladium‐catalyzed coupling reactions. This review focuses on recent advances in palladium‐catalyzed cross‐coupling reactions such as Suzuki, Heck, Stille, Sonogoshira etc. reactions of coumarin derivatives and covers the literature from 2001 to 2020.