Premium
Lanthanum isopropoxide catalyzed addition of activated nucleophiles to imines
Author(s) -
Yamamoto Yoshinori,
Fukui Hiroyuki,
Honda Yoshihiro
Publication year - 1995
Publication title -
applied organometallic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 71
eISSN - 1099-0739
pISSN - 0268-2605
DOI - 10.1002/aoc.590090515
Subject(s) - chemistry , nucleophile , catalysis , lanthanum , activated carbon , medicinal chemistry , imine , nitrogen atom , organic chemistry , group (periodic table) , adsorption
The addition of certain activated nucleophiles to activated imines is catalyzed by lanthanum isopropoxide. As activated nucleophiles, methylmalononitrile and methyl 2‐cyanopropanoate can be utilized. Imines having an electronwithdrawing group either at the carbon or at the nitrogen atom of the C=N double bond can be used; for example N ‐toluenesulfonylimines, N ‐(4‐methoxycarbonylphenyl)imines and α‐imino esters.