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Synthesis and psychotropic properties of 1‐triorganylsiloxy‐ and 1‐triorganylgermoxy‐germatranes
Author(s) -
Lukevics Edmunds,
Ignatovich Lubov,
Shilitalia,
Ǧērmane Skaidrīte
Publication year - 1992
Publication title -
applied organometallic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 71
eISSN - 1099-0739
pISSN - 0268-2605
DOI - 10.1002/aoc.590060303
Subject(s) - chemistry , stereochemistry
Triorganylsiloxy‐ and triorganylgermoxy‐germatranes have been prepared by the interaction of the easily available 1‐hydroxygermatrane with various hetaryl‐silanes and ‐germanes. The compounds were of the general structure:M = Si; X = S, CH = CH (viz. phenyl); n = 0,1,2 M = Ge; X = CH = CH (viz. phenyl); n = 0All siloxy‐ and germoxy‐germatranes obtained were subjected to psychotropic assays. Some of phenylsiloxygermatranes are effective for memory enhancement (inhibition of retrogradal amnesia by triphenylsiloxygermatrane was 80%).