Premium
Determination of arsenic compounds by high‐pressure liquid chromatography–graphite furnace atomic absorption spectrometry and thermospray mass spectrometry
Author(s) -
Cullen William R,
Dodd Matthew
Publication year - 1989
Publication title -
applied organometallic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 71
eISSN - 1099-0739
pISSN - 0268-2605
DOI - 10.1002/aoc.590030505
Subject(s) - chemistry , thermospray , arsenobetaine , arsenate , chromatography , mass spectrometry , arsenic , high performance liquid chromatography , graphite furnace atomic absorption , arsenite , iodide , inorganic chemistry , inductively coupled plasma mass spectrometry , selected reaction monitoring , tandem mass spectrometry , organic chemistry
Abstract Biologically important arsenic species such as arsenobetaine, arsenocholine iodide, tetramethylarsonium iodide, methylarsonic acid, and dimethylarsinic acid can be separated and quantitated by HPLC. The pH‐sensitive separations on a weak anion‐exchange column are described, as well as separations on a reverse‐phase column with the aid of tetrabutylammonium nitrate or heptanesulfonic acid as ion‐pairing agents. The thermospray mass spectra of these arsenicals in addition to those of sodium arsenate and an arsenosugar derivative are described. This technique is suitable for HPLC MS studies.