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Synthesis, storage, and transfer of [ 210 Pb]‐(CH 3 ) 3 PbCl across tomato fruit cuticle
Author(s) -
Blais J S,
Momplaisir G M,
Marshall W D
Publication year - 1989
Publication title -
applied organometallic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 71
eISSN - 1099-0739
pISSN - 0268-2605
DOI - 10.1002/aoc.590030109
Subject(s) - chemistry , iodide , acetic acid , decomposition , bromide , yield (engineering) , nuclear chemistry , hydrochloric acid , anhydrous , high performance liquid chromatography , ethylenediamine , chromatography , inorganic chemistry , organic chemistry , materials science , metallurgy
An improved synthetic route to [ 210 Pb]‐(CH 3 ) 3 PbCl is described in which chelated 210 Pb 2+ is methylated to [ 210 Pb]‐(CH 3 ) 4 Pb with methylmagnesium bromide (CH 3 MgBr) in the presence of methyl iodide. Controlled oxidation of the product with anhydrous hydrochloric acid and purification of the crude product by reversed‐phase high‐pressure liquid chromotography (HPLC) resulted in [ 210 Pb]‐(CH 3 ) 3 PbCl in 71% radiochemical yield. Whereas storage of the purified product at −10 °C resulted in complete conversion to Pb 2+ during one year, storage in 20% acetic acid at 4 °C resulted in less than 15% decomposition during six months. Periodic complexometric extractions to remove 210 Pb radioactive daughters ( 210 Bi, 100% β, E max = 1.16 MeV; 210 Po, 100% α, E = 5.305 MeV) from the storage solution did not alter the rate of decomposition. The rate of translocation of [ 210 Pb]‐(CH 3 ) 3 Pb + across an isolated tomato cuticle was approximately twice the rate of transfer of inorganic lead(II) and was not influenced by the presence of increasing amounts of disodium ethylenediamine‐tetra‐acetate.