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Synthesis of novel thiazolo[3,2‐ a ]chromeno[4,3‐ d ]pyrimidine‐6(7 H )‐ones by bioactive Fe 3 O 4 @gly@thiophen@Cu(NO 3 ) 2 as reusable magnetic nanocatalyst
Author(s) -
Hosseinzadegan Sara,
Hazeri Nourallah,
Maghsoodlou Malek Taher
Publication year - 2020
Publication title -
applied organometallic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 71
eISSN - 1099-0739
pISSN - 0268-2605
DOI - 10.1002/aoc.5797
Subject(s) - chemistry , thermogravimetric analysis , thermogravimetry , nuclear chemistry , scanning electron microscope , magnetic nanoparticles , fourier transform infrared spectroscopy , nanoparticle , pyrimidine , transmission electron microscopy , spectroscopy , analytical chemistry (journal) , derivative (finance) , infrared spectroscopy , nanotechnology , chemical engineering , stereochemistry , inorganic chemistry , organic chemistry , materials science , physics , quantum mechanics , engineering , composite material , financial economics , economics
In this study, new Fe 3 O 4 @gly@thiophen@Cu(NO 3 ) 2 magnetic nanoparticles were synthesized. The final product was used as an efficient and novel magnetic nanocatalyst for synthesizing new derivatives of thiazolo[3,2‐ a ] chromeno[4,3‐ d ]pyrimidine‐6(7 H ) in a short time and with higher efficiency. In the synthesis of Fe 3 O 4 @gly@thiophen@Cu(NO 3 ) 2 magnetic nanoparticles, the use of glycine proved an inexpensive and readily available coating for Fe 3 O 4 than previously reported materials, and the structure was confirmed using scanning electron microscopy, transmission electron microscopy, X‐ray diffraction, energy‐dispersive x‐ray (EDX) spectroscopy, EDX mapping, Fourier‐transform infrared spectroscopy, thermogravimetric analysis/derivative thermogravimetry, and vibrating sample magnetometry. The biological properties of magnetic nanoparticles were evaluated, and they exhibited acceptable antifungal and antibacterial properties in terms of minimum inhibitory concentration, minimum fungicidal concentration, and minimum bactericidal concentration.