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A green, efficient and recoverable CeO 2 /MWCNT nanocomposite catalyzed click synthesis of pyridine‐3‐carboxamides
Author(s) -
Harikrishna Singamsetty,
Robert Alice R.,
Ganja Himavathi,
Maddila Suresh,
Jonnalagadda Sreekantha B.
Publication year - 2020
Publication title -
applied organometallic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 71
eISSN - 1099-0739
pISSN - 0268-2605
DOI - 10.1002/aoc.5796
Subject(s) - chemistry , catalysis , ammonium acetate , aldehyde , nanocomposite , reusability , pyridine , solvent , organic chemistry , heterogeneous catalysis , condensation reaction , composite number , chemical engineering , combinatorial chemistry , high performance liquid chromatography , materials science , computer science , engineering , programming language , composite material , software
A facile, green and environmentally‐friendly protocol for the preparation of ceria doped multi‐walled carbon nanotubes (2.5%CeO 2 /MWCNTs) composite catalysts are developed. The synthesized catalyst materials have been characterized by using P‐XRD, SEM, TEM and BET analysis. Further, the composite was utilized as a highly efficient and reusable heterogeneous nano‐catalyst for the synthesis of pyridine‐3‐carboxamide derivatives by multicomponent condensation of acetoacetanilide, ammonium acetate, substituted aromatic aldehyde and ethyl cyanoacetate via one‐pot reaction under ethanol solvent conditions at R.T. The remarkable advantages of this green protocol exhibits operational simplicity, easy workup procedure, inexpensive, evading of toxic solvents, shorter reaction times (≤ 15 mins), excellent yields and also avoidance of column chromatography. Furthermore, the catalyst was recyclable and reusability endured for a minimum of six consecutive cycles without significant loss in the catalytic activity.