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Copper‐immobilized ionic liquid as an alternative to organic solvents in the one‐pot synthesis of bioactive dihydropyrano[ 2,3‐c ]pyrazole derivatives
Author(s) -
Ghafuri Hossein,
Kazemnezhad Leili Maede,
Esmaili Zand Hamid Reza
Publication year - 2020
Publication title -
applied organometallic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 71
eISSN - 1099-0739
pISSN - 0268-2605
DOI - 10.1002/aoc.5757
Subject(s) - chemistry , pyrazole , ionic liquid , catalysis , copper , solvent , combinatorial chemistry , one pot synthesis , carbon 13 nmr , organic chemistry
In this study, a novel Cu‐immobilized ionic liquid (IL)was designed, characterized, and employed as both promoter and solvent in the synthesis of some dihydropyrano[2,3‐ c ]pyrazoles. The synthesized ionic liquid was characterized by 1 H NMR, 13 C NMR, FTIR, ICP and EDX analysis and showed high catalytic activity to proceed the synthesis of bioactive dihydropyrano[2,3‐ c ]pyrazole derivatives. This method has the advantage of using the IL as a green medium for the synthesize of the products in high to excellent yields within short reaction times.