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Direct synthesis of completely unsymmetrical triarylmethanes via Fe(III) salt‐mediated in situ o ‐quinone methides process
Author(s) -
Yang Qi,
Wu RunShi,
Wu KeXin,
Gu YingChun,
Yu YaQin,
Xu DaZhen
Publication year - 2020
Publication title -
applied organometallic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 71
eISSN - 1099-0739
pISSN - 0268-2605
DOI - 10.1002/aoc.5716
Subject(s) - chemistry , chemoselectivity , salt (chemistry) , annulation , quinone , in situ , ligand (biochemistry) , combinatorial chemistry , molecule , organic chemistry , base (topology) , catalysis , mathematical analysis , biochemistry , receptor , mathematics
An efficient and straightforward synthetic approach to completely unsymmetrical triarylmethanes through the situ ‐generated o ‐quinone methides from readily available starting materials has been successfully developed. In the presence of an Fe(III) salt, three different aromatic rings, including salicylaldehydes, arylboronic acids, and arenes, were incorporated into one molecule in a single step under the base/ligand‐free conditions. The related reactions show high chemoselectivity and afford a variety of completely unsymmetrical triarylmethane products in good to excellent yields.