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Catalytic and antibacterial properties of 3‐dentate carboxamide Pd/Pt complexes obtained via a benign route
Author(s) -
Kiani Mahsa,
Bagherzadeh Mojtaba,
Meghdadi Soraya,
FadaeiTirani Farzaneh,
SchenkJoß Kurt,
Rabiee Navid
Publication year - 2020
Publication title -
applied organometallic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 71
eISSN - 1099-0739
pISSN - 0268-2605
DOI - 10.1002/aoc.5531
Subject(s) - chemistry , catalysis , cyclic voltammetry , palladium , aryl , antibacterial activity , heck reaction , nuclear chemistry , solvent , fourier transform infrared spectroscopy , coupling reaction , inorganic chemistry , medicinal chemistry , polymer chemistry , electrochemistry , organic chemistry , alkyl , physics , electrode , quantum mechanics , biology , bacteria , genetics
The complexes Pd II (qcq)(OAc) and Pt II (qcq)Cl have been synthesized using environmentally benign synthesized ligands and characterized by elemental analyses: Fourier transform infrared spectroscopy, UV–visible spectroscopy, 1 H NMR spectroscopy, and X‐ray diffraction. The catalytic activity of the complex was assessed, in different media, for the Mizoroki–Heck coupling reaction for typical aryl halides and terminal olefins under aerobic conditions. Since the base and the solvent were found to influence the efficiency of the reaction, reaction conditions, temperature, time, and the amount of K 3 PO 4 and a mixture of H 2 O/PEG, were optimized. We found, for the Mizoroki–Heck reaction coupling less reactive aryl chloride derivatives with olefins, promising activity for palladium catalysts. The electrochemical behavior of Hqcq and the Pd(II) complex was investigated by cyclic voltammetry and irreversible Pd II/I reductions were observed. Hqcq and the Pd(II) and Pt(II) complexes were also screened for their in vitro antibacterial activity. They showed promising antibacterial activity comparable to that of the antibiotic penicillin.