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TiO 2 Nanoparticles Immobilized on Carbon Nanotubes: An Efficient Heterogeneous Catalyst in Cyclocondensation Reaction of Isatins with Malononitrile and 4‐Hydroxycoumarin or 3,4‐Methylenedioxyphenol under Mild Reaction Conditions
Author(s) -
Abdolmohammadi Shahrzad,
Rasouli Nasrabadi Seyed Reza,
Dabiri Mohammad Reza,
Banihashemi Jozdani Sayed Mustafa
Publication year - 2020
Publication title -
applied organometallic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 71
eISSN - 1099-0739
pISSN - 0268-2605
DOI - 10.1002/aoc.5462
Subject(s) - malononitrile , chemistry , catalysis , aqueous solution , nanoparticle , aqueous medium , reaction conditions , carbon nanotube , heterogeneous catalysis , green chemistry , organic chemistry , combinatorial chemistry , reaction mechanism , nanotechnology , materials science
TiO 2 nanoparticles supported on carbon nanotubes (TiO 2 ‐CNTs) as an efficient heterogeneous catalyst was used for the synthesis of spiro[3,4′]1,3‐dihydro‐2 H ‐indol‐2‐one‐2′‐amino‐5′‐oxo‐4' H ,5' H ‐pyrano[3′,2′‐ c ]chromen‐3′‐yl cyanides and spiro[3,8′]1,3‐dihydro‐2 H ‐indol‐2‐one‐6′‐amino‐8' H ‐[1′,3′]dioxolo[4′,5′‐ g ]chromen‐7′‐yl cyanides via the cyclocondensation reaction of isatins with malononitrile and 4‐hydroxycoumarin or 3,4‐methylenedioxyphenol in aqueous media at room temperature. This reaction offers several sustainable and economic benefits such as high yields of products, convenient operation, and use of non‐toxic catalyst in water media.