Premium
Pyrazole‐3‐carboxylates assisted N ‐heterocyclic carbene palladium complexes: synthesis, characterization, and catalytic activities towards arylation of azoles with arylsulfonyl hydrazides
Author(s) -
Yang Jin
Publication year - 2020
Publication title -
applied organometallic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 71
eISSN - 1099-0739
pISSN - 0268-2605
DOI - 10.1002/aoc.5450
Subject(s) - chemistry , pyrazole , carboxylate , carbene , palladium , catalysis , medicinal chemistry , chelation , ligand (biochemistry) , carboxylic acid , stereochemistry , polymer chemistry , organic chemistry , biochemistry , receptor
Four mononuclear and dinuclear pyrazole‐3‐carboxylates assisted NHC–Pd complexes have been synthesized and characterized. Notably, the bridge‐cleavage reactions of [Pd( μ ‐Cl)(Cl)(NHC)] 2 with 1 H ‐pyrazole‐3‐carboxylic acid afforded dinuclear complexes [(NHC)Pd( μ ‐1 H ‐pyrazolato‐3‐carboxylate)] 2 , in which the 1 H ‐pyrazolato‐3‐carboxylate was employed as a N^N^O dianionic chelating and bridging ligand. To further explore the structural features and catalytic properties of the complexes, 1‐methyl‐1 H ‐pyrazole‐3‐carboxylic acid was introduced into the coordination with [Pd( μ ‐Cl)(Cl)(NHC)] 2 and the corresponding mononuclear complexes (NHC)PdCl(1‐methyl‐1 H ‐pyrazole‐3‐carboxylate) were obtained. The catalytic properties of the complexes in desulfitative arylation of azoles with arylsulfonyl hydrazides were initially investigated.