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CuI‐catalyzed direct synthesis of diaryl thioethers from aryl boronic acids and arylsulfonyl chlorides
Author(s) -
Huang Keke,
Yang Min,
Lai XiaoJing,
Hu Xin,
Qiu Guanyinsheng,
Liu JinBiao
Publication year - 2020
Publication title -
applied organometallic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 71
eISSN - 1099-0739
pISSN - 0268-2605
DOI - 10.1002/aoc.5385
Subject(s) - chemistry , aryl , boronic acid , catalysis , chloride , organic chemistry , combinatorial chemistry , sulfur , alkyl
A CuI‐catalyzed direct coupling of aryl boronic acids with arylsulfonyl chlorides for the preparation of diaryl thioethers was developed. The reaction is initiated by a PPh 3 reduction of the arylsulfonyl chloride, followed by a CuI‐catalyzed C–S coupling with an aryl boronic acid. Various arylsulfonyl chlorides can directly serve as a sulfur source in this mild and efficient reaction giving the desired products in moderate to good yields. Moreover, this practical method has also been applied to the thioetherification of aryl iodides and acetylacetones.