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Synthesis of Pyrazolo‐[4́,3́:5,6]pyrido[2,3‐d]pyrimidine‐diones Catalyzed by a Nano‐sized Surface‐Grafted Neodymium Complex of the Tungstosilicate via Multicomponent Reaction
Author(s) -
Daraie Mansoureh,
Heravi Majid M.,
Mirzaei Masoud,
Lotfian Nahid
Publication year - 2019
Publication title -
applied organometallic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 71
eISSN - 1099-0739
pISSN - 0268-2605
DOI - 10.1002/aoc.5058
Subject(s) - chemistry , catalysis , hydrazine (antidepressant) , barbituric acid , ethyl acetoacetate , hydrate , hybrid material , lanthanide , aryl , heterogeneous catalysis , ammonium acetate , powder diffraction , adsorption , pyrimidine , inorganic chemistry , polymer chemistry , organic chemistry , stereochemistry , crystallography , ion , alkyl , high performance liquid chromatography , chromatography
An inorganic–organic hybrid based on lanthanide clusters and Keggin type polyoxometalates (POMs) (Na[Nd (pydc‐OH)(H 2 O) 4 ] 3 }[SiW 12 O 40 ]) was used the first time as trinuclear catalyst for one pot synthesis of pyrazolo[4́́,3́:5,6]pyrido[2,3‐ d ]pyrimidine‐diones, via two different four and five‐component reactions involving hydrazine hydrate, ethyl acetoacetate, aryl aldehydes, and 6‐amino‐1,3‐dimethyl uracil or barbituric acid with ammonium acetate as alternative materials in green condition. To evaluate potential application of the as‐made hybrid in adsorption and separation processes, nitrogen adsorption was performed at 77 K through simulation study. The hybrid catalyst was further characterized via powder X‐ray diffraction (PXRD) at room temperature which indicated the good phase purity of the catalyst. The results show that the catalytic activity of the hybrid catalyst has increased relative to each parent component due to the special interaction between Keggin anions and pydc‐OH ligands.