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Highly efficient and green approach for the synthesis of spirooxindole derivatives in the presence of novel Brønsted acidic ionic liquids incorporated in UiO‐66 nanocages
Author(s) -
MirhosseiniEshkevari Boshra,
Ghasemzadeh Mohammad Ali,
Esnaashari Manzarbanoo
Publication year - 2019
Publication title -
applied organometallic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 71
eISSN - 1099-0739
pISSN - 0268-2605
DOI - 10.1002/aoc.5027
Subject(s) - chemistry , nanocages , catalysis , oxindole , ionic liquid , reusability , imidazole , heterogeneous catalysis , combinatorial chemistry , barbituric acid , brønsted–lowry acid–base theory , organic chemistry , software , computer science , programming language
An efficient and green approach is reported for the rapid synthesis of spirocyclic 2‐oxindole using triethylenediamine or imidazole Brønsted acidic ionic liquids supported in Zr metal–organic framework (TEDA/IMIZ‐BAIL@UiO‐66) as a novel, superior and retrievable heterogeneous catalyst under ultrasonic irradiation. Heterocyclic compounds including pyrido[2,3‐ d :6,5‐ d ′]dipyrimidines and indeno[2′,1′:5,6]pyrido[2,3‐ d ]pyrimidines were obtained by the one‐pot condensation reaction of 6‐amino‐1,3‐dimethyluracil, isatins and cyclic 1,3‐diketone (barbituric acid or 1,3‐indanedione). The reusability of the catalyst, low catalyst loading, short reaction times, excellent yields, simple work‐up, and use of sonochemical procedure as a mild process and an alternative energy source are some of the advantages of this method. Furthermore, the novel heterogeneous nanocomposite was fully characterized using various techniques.