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Palladium‐catalyzed decarboxylative coupling of α,β‐unsaturated carboxylic acids with aryl tosylates
Author(s) -
Zhang Wei,
Chen Gairong,
Wang Kaikai,
Xia Ran
Publication year - 2019
Publication title -
applied organometallic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 71
eISSN - 1099-0739
pISSN - 0268-2605
DOI - 10.1002/aoc.4914
Subject(s) - chemistry , decarboxylation , aryl , palladium , catalysis , substrate (aquarium) , carboxylic acid , combinatorial chemistry , selectivity , coupling (piping) , organic chemistry , simplicity , mechanical engineering , alkyl , oceanography , engineering , geology , philosophy , epistemology
We report a general method for selective cross‐coupling of α,β‐unsaturated carboxylic acids with aryl tosylates enabled by versatile Pd(II) complexes. This method features the general cross‐coupling of ubiquitous α,β‐unsaturated carboxylic acids by decarboxylation. The transformation is characterized by its operational simplicity, the use of inexpensive, air‐stable Pd(II) catalysts, scalability and wide substrate scope. The reaction proceeds with high trans selectivity to furnish valuable ( E )‐1,2‐diarylethenes.