Premium
Ultrasound‐assisted green synthesis of Cu‐based complexes of β ‐cyclodextrin and their SOD‐like activity
Author(s) -
NikzadKojanag Behnaz,
Pirouzmand Mahtab,
HosseiniYazdi Seyed Abolfazl
Publication year - 2019
Publication title -
applied organometallic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 71
eISSN - 1099-0739
pISSN - 0268-2605
DOI - 10.1002/aoc.4861
Subject(s) - chemistry , pyrogallol , autoxidation , nuclear chemistry , cyclodextrin , superoxide dismutase , radical , antioxidant , zinc , copper , scanning electron microscope , organic chemistry , physics , quantum mechanics
A novel Cu–Zn β ‐cyclodextrin (CuZn/ β ‐CD) model compound was synthesized under ultrasound irradiation to mimic the functionality of copper zinc superoxide dismutase (CuZnSOD). For comparison, Cu/ β ‐CD and Zn/ β ‐CD complexes were also synthesized via a sonochemical approach. The obtained complexes were characterized by FTIR, ICP‐OES, UV–vis and Scanning electron microscopy‐Energy dispersive X‐ray (SEM‐EDX) techniques. The SOD activity of the complexes was evaluated by a pyrogallol autoxidation method. These enzyme‐mimetic materials scavenge ambient free radicals, with the potential to provide significant antioxidant protection (scavenging ability > 70%).
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom