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Toxicological and pesticidal studies on novel bioactive sulfonamide imine organotin(IV) complexes
Author(s) -
Jain Mukta,
Singh R. V.
Publication year - 2003
Publication title -
applied organometallic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 71
eISSN - 1099-0739
pISSN - 0268-2605
DOI - 10.1002/aoc.484
Subject(s) - chemistry , ligand (biochemistry) , imine , denticity , monobasic acid , monomer , sulfonamide , nuclear magnetic resonance spectroscopy , carbon 13 nmr , proton nmr , tin , dimethylformamide , stereochemistry , metal , polymer chemistry , organic chemistry , solvent , polymer , biochemistry , receptor , catalysis
Toxicological, pesticidal and stereochemical aspects of organotin(IV) complexes with a sulfonamide imine ligand having an N ∩ N donor system are described with the support of elemental analysis, IR, UV, 1 H NMR, 13 C NMR and 119 Sn NMR spectroscopy. The spectral data suggest that the ligand acts in a monobasic bidentate manner coordinating through the nitrogen atom. The complexes have been characterized on the basis of molecular weight determinations, conductivity measurements, and magnetic measurements. The isolated products are coloured solids, soluble in dimethylsulfoxide, dimethylformamide (DMF) and methanol. All the complexes are monomeric in nature, as indicated by their molecular weight determinations. Conductivity measurements in dry DMF show them to be non‐electrolytes. From the analyses of these studies the donor sites of the ligand are located and the geometries of the donor environment around the tin(IV) acceptor centres proposed. The ligand and its metal complexes are tested in vitro against a number of pathogenic fungal and bacterial strains and the findings are discussed. Emphasis has been given to the nematicidal properties. Copyright © 2003 John Wiley & Sons, Ltd.