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Synthesis and characterization of novel chelated dimethylamino lithium arylamide dimers: molecular structure of [1‐LiNPhCHPhCH 2 ‐2‐NMe 2 C 6 H 4 ] 2
Author(s) -
AlMasri Harbi Tomah,
Sieler Joachim,
HeyHawkins Evamarie
Publication year - 2003
Publication title -
applied organometallic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 71
eISSN - 1099-0739
pISSN - 0268-2605
DOI - 10.1002/aoc.475
Subject(s) - chemistry , lithium (medication) , chelation , ether , ring (chemistry) , diethyl ether , crystal structure , nuclear magnetic resonance spectroscopy , solvent , stereochemistry , medicinal chemistry , crystallography , organic chemistry , medicine , endocrinology
The reaction of 1‐NHPhCHPh‐2‐NMe 2 C 6 H 4 ( 1 ) and 1‐NHPhCHPhCH 2 ‐2‐NMe 2 C 6 H 4 ( 2 ) with n ‐BuLi in diethyl ether gave the solvent‐free chelated dimethylamino lithium amides [1‐LiNPhCHPh‐2‐NMe 2 C 6 H 4 ] 2 ( 3 ) and [1‐LiNPhCHPhCH 2 ‐2‐NMe 2 C 6 H 4 ] 2 ( 4 ). The lithium amides 3 and 4 were characterized by 1 H, 7 Li, and 13 C NMR spectroscopy. A crystal structure determination was carried out on 4 , which is the first example of a structurally characterized solvent‐free dimeric chelated dimethylamino lithium arylamide with three‐coordinate lithium centers that contains a seven‐membered chelate ring. Copyright © 2003 John Wiley & Sons, Ltd.